KB
Karriere bei Robert Bosch Krankenhaus GmbH
Research Scientist

Post Doctoral Research Scientist - Bioinformatics (m/f/d)

On-siteMidResearch Scientistposted 8mo ago
Role summaryAI-generated

This postdoctoral role focuses on advancing cancer research through advanced bioinformatics, particularly in single-cell and spatial transcriptomics, to decode tumor microenvironment dynamics in renal cell carcinoma. The position emphasizes innovative data integration, statistical modeling, and high-impact scientific communication in a clinical research setting.

Skills required

About this role

  • Bioinformatic analysis of multi-omics data with focus on single-cell and spatial transcriptomics RNA sequencing data to elucidate the tumor microenvironment and its influence on cancer progression and metastasis in renal cell carcinoma
  • Integrating multi-omics data sets (e.g. genomics, metabolomics) of primary tumors and metastasis through innovative bioinformatics analysis applicable to high-dimensional data
  • Integrated analysis of clinical phenotypes and -omics data using biostatistics and bioinformatics
  • Application of a broad spectrum of established tools and development of new computational solutions with focus on single-cell and spatial transcriptomics RNA seq and data integration
  • Enthusiasm to present scientific results at international conferences and writing papers for high-quality publications to ensure greatest possible success in your career track

Qualifications

  • Doctoral degree (PhD) in bioinformatics, applied bioinformatics or a related discipline
  • Experience and strong background in the analysis of spatial transcriptomics and single-cell RNA sequencing data, as well as multi-omics datasets (e.g. proteomics, transcriptomics, genomics), including data interpretation.
  • Strong interest in life science applications with focus on oncology and personalized medicine
  • Strong programming skills in R and in Python
  • Solid background in cancer biology
  • Knowledge in biostatistics would be beneficial
  • Excellent English written and oral communication skills, as well as expertise in preparation of scientific manuscripts.

Additional Information

We offer:

  • The opportunity to work in an interactive team of bioinformaticians, clinicians and biologists.
  • State-of-the-art equipment and technologies for a wide range of different applications (genomics, transcriptomics, metabolomics) and expert knowledge within the different core facilities (e.g. core facility “Biostatistics/Bioinformatics, Pharmacometrics and Digital Science”) at the institute
  • The opportunity to communicate scientific results at international conferences and to participate in workshops
  • An initial contract for 3 years and flexible starting date (earliest starting date as of now)

For further information please contact Prof. Dr. Matthias Schwab (phone 0711-8101-3700) or Dr. Elke Schaeffeler (phone 0711-8101-3729).

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